In Silico Dreams: How Artificial Intelligence and Biotechnology Will Create the Medicines of the Future
- Length: 352 pages
- Edition: 1
- Language: English
- Publisher: Wiley
- Publication Date: 2021-08-31
- ISBN-10: 1119745578
- ISBN-13: 9781119745570
- Sales Rank: #2733509 (See Top 100 Books)
Learn how AI and data science are upending the worlds of biology and medicine
In Silico Dreams: How Artificial Intelligence and Biotechnology Will Create the Medicines of the Future delivers an illuminating and fresh perspective on the convergence of two powerful technologies: AI and biotech. Accomplished genomics expert, executive, and author Brian Hilbush offers readers a brilliant exploration of the most current work of pioneering tech giants and biotechnology startups who have already started disrupting healthcare. The book provides an in-depth understanding of the sources of innovation that are driving the shift in the pharmaceutical industry away from serendipitous therapeutic discovery and toward engineered medicines and curative therapies.
In this fascinating book, you’ll discover:
- An overview of the rise of data science methods and the paradigm shift in biology that led to the in silico revolution
- An outline of the fundamental breakthroughs in AI and deep learning and their applications across medicine
- A compelling argument for the notion that AI and biotechnology tools will rapidly accelerate the development of therapeutics
- A summary of innovative breakthroughs in biotechnology with a focus on gene editing and cell reprogramming technologies for therapeutic development
- A guide to the startup landscape in AI in medicine, revealing where investments are poised to shape the innovation base for the pharmaceutical industry
Perfect for anyone with an interest in scientific topics and technology, In Silico Dreams also belongs on the bookshelves of decision-makers in a wide range of industries, including healthcare, technology, venture capital, and government.
Cover Table of Contents Title Page Introduction What Does This Book Cover? Reader Support for This Book CHAPTER 1: The Information Revolution's Impact on Biology A Biological Data Avalanche at Warp Speed Biology's Paradigm Shift Enables In Silico Biology Sequencing the Human Genome Computational Biology in the Twenty-First Century Omics Technologies and Systems Biology Notes CHAPTER 2: A New Era of Artificial Intelligence AI Steps Out of the Bronx From Neurons and Cats Brains to Neural Networks Machine Learning and the Deep Learning Breakthrough Limitations on Artificial Intelligence Notes Recommended Reading CHAPTER 3: The Long Road to New Medicines Medicine's Origins: The Role of Opium Since the Stone Age Industrial Manufacturing of Medicines Paul Ehrlich and the Birth of Chemotherapeutic Drug Discovery The Pharmaceutical Industry: Drugs and War—New Medicines in the Twentieth Century The Pharmaceutical Business Model in the Twenty-First Century Notes Recommended Reading CHAPTER 4: Gene Editing and the New Tools of Biotechnology Molecular Biology and Biological Information Flow Manipulating Gene Information with Recombinant DNA Technology Genetics, Gene Discovery, and Drugs for Rare Human Diseases Second-Generation Biotechnology Tools: CRISPR- Cas9 and Genome Editing Technologies Human Genome Editing and Clinical Trials Biotechnology to the Rescue: Vaccine Development Platforms Based on Messenger RNA Recommended Reading Notes CHAPTER 5: Healthcare and the Entrance of the Technology Titans Digital Health and the New Healthcare Investment Arena Assessing the Tech Titans as Disruptors in Healthcare Echoes of the Final Frontier Notes CHAPTER 6: AI-Based Algorithms in Biology and Medicine Recognizing the Faces of Cancer AI for Diseases of the Nervous System: Seeing and Changing the Brain Notes CHAPTER 7: AI in Drug Discovery and Development A Brief Survey of In Silico Methods in Drug Discovery AI Brings a New Toolset for Computational Drug Design A New Base of Innovation for the Pharmaceutical Industry Summary Notes CHAPTER 8: Biotechnology, AI, and Medicine's Future Building Tools to Decipher Molecular Structures and Biological Systems Neuroscience and AI: Modeling Brain and Behavior Engineering Medicines with Biotechnology and AI Notes Glossary Index Copyright About the Author About the Technical Editor Acknowledgments End User License Agreement
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