Gene Regulation and Therapeutics for Cancer
- Length: 328 pages
- Edition: 1
- Language: English
- Publisher: CRC Press
- Publication Date: 2021-03-22
- ISBN-10: 1138712426
- ISBN-13: 9781138712423
- Sales Rank: #0 (See Top 100 Books)
Differential gene regulation and targeted therapy are the critical aspects of several cancers. This book covers specific gene regulation and targeted therapies in different malignancies. It offers a comprehensive assessment of the transcriptional dysregulation in cancer, and considers some examples of transcriptional regulators as definitive oncogenic drivers in solid tumors, followed by a brief discussion of transcriptional effectors of the programs they drive, and discusses its specific targets. Most targeted therapeutics developed to date have been directed against a limited set of oncogenic drivers, exemplified by those encoding cell surface or cytoplasmic kinases that function in intracellular signaling cascades.
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